Subject(s)
COVID-19/diagnosis , Jaundice/etiology , Liver/pathology , Systemic Inflammatory Response Syndrome/diagnosis , Bone Marrow/pathology , C-Reactive Protein/analysis , COVID-19/complications , Cholestasis/diagnosis , Diagnosis, Differential , Humans , Male , Middle Aged , Pruritus/etiology , Systemic Inflammatory Response Syndrome/complicationsSubject(s)
COVID-19/complications , Cholangitis, Sclerosing/etiology , Cholestasis/etiology , Jaundice, Obstructive/etiology , COVID-19/diagnosis , Cholangiopancreatography, Endoscopic Retrograde , Cholangitis, Sclerosing/diagnosis , Cholangitis, Sclerosing/therapy , Cholestasis/diagnosis , Cholestasis/therapy , Critical Illness , Humans , Jaundice, Obstructive/diagnosis , Jaundice, Obstructive/therapy , Male , Middle Aged , Prognosis , Syndrome , Time FactorsABSTRACT
The COVID-19 outbreak has spread across the globe at an alarming rate. As the pandemic escalates, experience of COVID-19 in pregnant women is accumulating. We present a case of COVID-19 pneumonia in a 28-week pregnant woman with a known low lying placenta. The patient had deranged liver function tests at presentation, along with elevated bile acids. We discuss the differential diagnosis of these findings, and the possible mechanisms of hepatic injury in COVID-19. The low lying placenta in this patient meant that we had to carefully consider the application of recommendations for thromboprophylaxis in pregnant COVID-19 patients. With supportive management, this patient improved enough to be discharged, and has gone on to deliver a healthy neonate at term.